The chapel of S. Sebastião is one of the monuments in Alvito that is part of the Fresco Route (see information about the Fresco Route), due to the beauty and heritage importance of the fresco paintings that can be seen inside. Located in the Rossio area, the chapel was probably built before 1535, although its authorship is unknown. It is a Manueline style building, with Mudejar influences (similar to the chapel of S. Brás, in Évora). The plan is simple, consisting of a single nave and a main chapel. The vaults of both the nave and the main chapel are painted in fresco, with figures of musical angels and are believed to have been designed by José de Escobar (a resident of Évora).