Neppermin was first mentioned in a document in 1254 as "Neprimin". In this document, the dukes Barnim I and Wartislaw III testify. the exchange of villages (including Neppermin) by knight Tammo. The place name is of Slavic origin and means something like (place at) standing water, which refers to the location on the backwater. At the time of the first documentary mention, the place had already existed as a manor for a long time.
After 1254, the possessions were transferred to the Grobe monastery near the city of Usedom. In 1309 the Grobe monastery was relocated to Pudagla. In 1402 the Pudagla Monastery acquired land in Neppermin. This fact is unclear whether the ownership in Neppermin changed in the meantime, or land was added.
In 1858 the village was partially destroyed in a fire. In 1899, the "Imperial Oak", which still exists today, was planted in honor of Kaiser Wilhelm II at the crossroads in Balm.
The flood of the Baltic Sea in 1872 also caused severe damage in Neppermin. Another time the place was partially flooded in the New Year's Eve storm surge in 1912.
At the beginning of the 20th century, the towns in the Usedom “hinterland” began to benefit from the increasing bathing tourism in the “imperial baths” in the northeast. This made better transport connections necessary. In 1905 the road to Benz and further into Dargen, located east of the Szczecin Lagoon, was built. A paved road to Balm (also part of Benz today) had already been built the year before. In 1912 Neppermin was connected to the power grid.
In 1931 the construction of the road from Mellenthin to Schmollensee via Neppermin began (former state road L 265, today federal road 111). The flyover that still exists today was built in Neppermin. In 1934 the Neppermin Volunteer Fire Brigade was founded.
On July 1, 1950, the previously independent municipality of Balm was incorporated.
From 1991 to 1993 the modern 300 meter long promenade was laid out on the Nepperminer See. In 1993 the campsite, also directly on Lake Neppermin, was inaugurated. In 1998, a 120 hectare golf course with a hotel and infrastructure was built in the municipality on Lake Balmer. In 2004 the municipality of Neppermin was integrated into the municipality of Benz.