The street begins in the Tiergarten district in front of the Brandenburg Gate on the border with the Mitte district at Platz des 18. März as an extension of the Unter den Linden boulevard. It runs through the Grosser Tiergarten and is interrupted there by the Grosser Stern. It crosses the Landwehrkanal with the Charlottenburger Bridge and reaches the Charlottenburg district. There it is flanked by the Charlottenburger Gate, which is a counterpart to the Brandenburg Gate in terms of the border of the Tiergarten. To the west it runs past the Federal Office for Building and Regional Planning, cuts through the main campus of the Technical University and ends at Ernst-Reuter-Platz.
Straße des 17. Juni is three lanes in both directions, partly four lanes. The directional lanes are structurally separated by a central reservation. At the Grosser Stern the road widens to up to six lanes and a wide shoulder.
What is striking is the existence of parking spaces on the central reservation and on the edge of the road, which many visitors to the Tiergarten can use as free parking, in contrast to the areas with parking management in the inner city areas.
The current design - which is now a listed building - especially the typical street lamps, was largely co-designed by Albert Speer. This continues in a westerly direction, where the uniform street is then called Bismarckstrasse (up to Sophie-Charlotte-Platz) or Kaiserdamm (up to Theodor-Heuss-Platz).
Of the previously planned development outside the Tiergarten, only the current Ernst-Reuter-Haus, the headquarters of the Federal Office for Building and Regional Planning, has been realized.