In 1892, Prof. Dr. Hermann Krause from Berlin acquired land on which a rehabilitation clinic stands. He built a villa and a horse stable there. In 1902, he sold his property under the name Hohenelse to the Brandenburg State Insurance Institute. In 1904, it became a convalescent home. During the First World War, wounded soldiers were treated here, and during the subsequent period of inflation, the clinic served as a convalescent home for children and to care for people with malnutrition. The home was forced to close in 1931. In the 1930s, the complex was first converted into a sports school for the SA and then used as an educational facility for German children who had grown up abroad. However, from 1940 onwards, part of the building complex was again used as a military hospital.
From 1966 onwards, a fundamental transformation took place from a pulmonary clinic to a dietary sanatorium. Diseases of the stomach, intestines, liver, gallbladder, and pancreas were treated there.
In the 1980s, the focus shifted to diabetes mellitus.
In 1994, the foundation stone was laid for a new building. With the opening of the new complex, orthopedic diseases were also treated in addition to diabetes. Since 2020, Hohenelse has also been a teaching clinic for nutritional medicine.