The road branches off from the Drum național 66 (European route 79) to the west at the southern edge of the mining town of Petroșani (Petroschen) and leads in the valley of the Jiu de Vest (Western Schil) via Vulcan (Wolkersdorf), Lupeni (Schylwolfsbach) and Uricani to Câmpu lui Neag, where the asphalt road ends, and continues between the Retezat Mountains to the north and the Vâlcan Mountains to the south through the Domogled-Valea Cernei National Park, follows the valley of the Cerna downstream and ends at Tațu at the confluence with the Drum național 67D.
The length of the road is around 105 kilometers, of which only the eastern 28 kilometers are asphalted.