It can be assumed that there was already a church in Egenhausen around the year 1000. The origins of the first proven place of worship go back to the late Middle Ages.
Today's church is probably one of the most beautiful late rococo churches in Lower Franconia. It was built in 1766 on behalf of Prince Bishop Friedrich von Seinsheim according to plans by Johann Michael Fischer, who was a student of the great master builder Balthasar Neumann.
The master bricklayers were Johannes Bährmann from Schraudenbach and Nikolaus Fälch from Bergrheinfeld. In addition, there were all the sculptors and stonemasons from Egenhausen who worked on the local sandstone. The portal coat of arms of the Prince Bishop of Würzburg and Bamberg Adam Friedrich von Seinsheim (1755-1779) is a duplicate. The damaged original was set up in the parish garden. The rococo cartouche shows the following inscription: 1764 "this house may have risen under this sign (e.g. coat of arms/family) and this stone can speak as sufficient witness." In the lateral niches are the figure of the church patron John the Baptist on the left and John on the right the Evangelist. The center of the pediment is decorated with the figure of Jesus Christ as the Good Shepherd. The caption: "eCCe agnuVs Del posItVs In gLorla honore Magna" - "Behold, the Lamb of God is made famous by his great merit." This is a so-called chronostichon, a verse that contains a year. CCVDIVILM = 1762.
The cemetery just north of the church is arguably unique among all cemeteries in the country. Even today, only local sandstone is used for the tombstones, which is stipulated in the cemetery regulations. Parts of the cemetery are under monument protection. After various changes in the years 1840, 1870 and 1920, the cemetery was completely redesigned in 1937 according to his plans by Pastor Adam Vogt, who worked as a pastor in Egenhausen from 1912 to 1949. In 1962, the entire cemetery was awarded a special prize in a competition organized by the German Horticultural Society as being exemplary in Germany. The fencing of the new part of the cemetery from local sandstone blocks was done by the people of Egenhausen themselves.