Ascott House, sometimes referred to as simply Ascott, is a Grade II* listed building in the hamlet of Ascott near Wing in Buckinghamshire, England. It is set in a 3,200-acre (13 km2) estate.
Ascott House was originally a farm house, built in the reign of James I and known as "Ascott Hall". In 1873 it was acquired by Baron Mayer de Rothschild (of the neighbouring Mentmore Towers estate). The Rothschild family had begun to acquire vast tracts of land in Buckinghamshire earlier in the century, on which they built a series of large mansions from 1852 onwards. Baron Mayer gave the house at Ascott to his nephew Leopold de Rothschild, who transformed it over the following decades into the substantial, but informal, country house it is today.