Built in the city center in 1910, in an eclectic style inspired by Venetian Gothic, it was commissioned by the banker and entrepreneur Emanuele Fizzarotti and designed by the architect Ettore Bernich, a leader of Italian eclecticism.[1] The palace preserves richly decorated rooms inside, each with a specific artistic style and the use and association of different materials and techniques. Built above the underground spring "Mare Isabella", Palazzo Fizzarotti has several architectural layers. Inside, 13th-century structures dating back to old convents and refreshment stations outside the walls of the medieval city are visible. In 1850, with the demolition of the medieval walls and the expansion of the city through the Murattiano district, two areas of land were connected by Nicola Lagattola. In November 1858 the Lagattola heirs sold the land to Nicola Loiacono who built the ground floor and first floor in Baroque style, demolishing and incorporating the old 13th-century structures. The last Loiacono heir, Rosa, sold the entire complex in 1879 to the entrepreneur Emanuele Fizzarotti who modified it, raising the second and third floors and applying a Venetian Gothic façade.
Following the death of Emanuele Fizzarotti in 1926, the building first became, in the 1930s, the property and headquarters of the Banca del Fucino and then, after the Allied landing in southern Italy, the headquarters of the Circolo Ufficiali Alleati. Between 1960 and 1980 it was instead the headquarters of the offices of the European Community.
Today Palazzo Fizzarotti is also home to the Poli Archive, which preserves the contribution of Giosuè Poli from Molfetta, sports manager, organizer and athlete, in the social restructuring of the Apulian territory and of Italian sport, during and after the Second World War.