Located in the countryside of the municipality of the same name in the province of Isernia, it was established with D.M. 04/20/1982. Initially it extended 540 Ha, but following the D.M. 30.12.1983 it was brought to 552 hectares, almost half of the entire municipal territory. The altitude varies between 640 and 1130 m above sea level and the prevailing exposure of the territory is South South-West. The orography varies between soft and harsher environments up to pronounced vertical leaps. The former have a clayey-schistose or soft and friable calcareous geological matrix, the others are formed by massive banks of compact limestone very evident upstream of the town. The reserve is located in central-western Molise, borders the countryside of Isernia and is about 50 km from Campobasso. The paths that skirt and cross it allow the visitor a complete observation for a long range. Peculiar is the geographical position of the Pesche countryside: it ranges over the city of Isernia and the Volturno river valley, the Matese and Mainarde mountains and the mountains overlooking the Roccaraso ski resort. Precisely to better highlight this panoramic feature, some ancient high-altitude mule tracks are being restored, above all improving the bottom, to allow access to the reserve also for hikers and visitors on mountain bikes, as well as to improve surveillance and administration in general.