The monastery was probably founded in the early to mid-13th century. The founders of the monastery were the Truchsess von Alzey. The first documentary mention was made in 1247. The monastery was incorporated into the Disibodenberg monastery that supervised it. However, the visitations were carried out from 1265 by the Eberbach monastery, to whose filiation Disibodenberg belonged.
The monastery was sponsored by the von Löwenstein family. In 1248 they transferred the tithe and the patronage of the parish church of Spiesheim. From 1296 the monastery is the family burial place.
Many of the members of the convent came from the regional noble families who made large donations to the monastery.
The monastery was founded in 1566 by Elector Friedrich III. lifted by the Palatinate in the course of the Reformation and converted into a stately home. At this point in time the size of the convent, as in many other monasteries, had already decreased significantly.
Sion was not the only Cistercian convent in the vicinity of Mauchenheim. Even older was the Paradies monastery, which was presumably located in the town.