Founded in 1408 by the disciple of Sergius of Radonezh, the Reverend Ferapont, after whom it was named.
Dedicated to the Nativity of the Virgin Mary, since this holiday was especially honored by Prince Andrei, at whose request the monastery was built.
The first stone cathedral in honor of the Nativity of the Virgin Mary stood in the Luzhetsky Monastery until the beginning of the 16th century, after which it was dismantled, and in its place, in 1524-1547, a new, five-domed one was built, which has survived to this day.