A Roman Catholic parish church belonging to the parish of St. Nicholas in Skwierzyna, Rokitno deanery, Zielona Góra-Gorzów diocese, Szczecin-Kamień metropolitan area, located in Skwierzyna, Międzyrzecz County, Lubusz Voivodeship. Built in the 19th century, some of the walls are much older, dating back to the 15th or even the 13th century. It is the only structure to have survived from the town's original medieval urban layout. The church is one of eleven sanctuaries belonging to the Zielona Góra-Gorzów diocese.
The first mention of St. Nicholas Church in Skwierzyna (then a settlement called Skwirzyna) dates from 1226. Part of the walls in the chancel, which survive in fragments, date from around this time.
In the 15th century, a new building was built on the site of the old church, this time entirely of brick. The plan of the original building almost entirely reflects the present-day appearance of the church. In 1507, St. Nicholas the Bishop became the church's patron saint.
Thirty-three years later, in 1540, St. Nicholas' Church became a Protestant church. At that time, most of Skwierzyna's residents were Protestant. Consequently, Stanisław Myszkowski, the starost of Międzyrzecz, handed the church over to them. This status remained until 1605, when Wawrzyniec Goślicki, the bishop of Poznań, intervened with Jan Zamojski, the starost of Międzyrzecz, regarding the church. The church official demanded that the church be returned to Catholic ownership.
A thorough renovation of the building took place between 1861 and 1863, giving it its present appearance. The new structure was consecrated on May 17, 1863, by Franciszek Stefanowicz, the auxiliary bishop of Poznań.
The church was spared from being burned down after the Russians (Soviets) entered the city in 1945 because they used the church as a warehouse for various equipment confiscated from the residents.